Laos is very safe in terms of crime but not so safe when it comes to medical facilities and transportation safety. Also more than 100 people a year die of unexploded bombs and mines left from the American war so stay on trodden paths. If you need seriouse medical help seek attention in Thailand. None of these are reasons to not visit and in general almost everybody is fine, especially along tourist routes. For a very complete list of what to look out for visit the US state department site www.travel.state.gov/travel/cis_pa_tw/cis/cis_946.html
To minimize (hardly existing) risk just go by speed-boat on the Mekong if you´re really in a hurry. And the ladnscape is more enjoyable travelling by slow-boat.
The speed boats are fast but can be dangerous if the water levels are low. Passengers are given motorbike helmets to wear because these little boats are like canoes on red bull. they are crazy fast so be careful. On the other hands, the slow boats are very scenic but very uncomfortable for westerners because the seats are made for small size asian people!
do you know what vaccinations, medical things you really need to do for two weeks travel in thailand and laos. We're going Bangkok chiang rai slow boat to luang prabang vang vieng vientiane bangkok? What's really necessary?
The days for having a battery of injections (typhoid, typhus, cholora, etc) are thankfully gone. Talk with your Dr. about getting a "gamma globulin" injection to boost your immune system prior to leaving. If you're going to be traveling on the cheap you may also want to investigate the Hepatitus-A vaccine. Drink only bottled liquids and resist using ice in drinks except at the higher priced tourist restaurants and hotels. Some bottled water sources are even suspect, safer to stick with beer and coke.
Actually, you don't need Malaria Tablets and rabies vaccination while you are traveling in Laos. But, you need mosquito repellant with you all the time. If you have rabies vaccination available in your country, it is worth to have one before traveling to Laos.
For more quiries, you can post your questions to info@laoetravel.com